Cell Signaling Analysis Assignment
In 2013, the Nobel Prize in Physiology or Medicine was awarded to James Rothman, Randy Schekman, and Thomas Sudhof for their pioneering research in cell signaling pathways.Cell Signaling Analysis Assignment Together, they were able to solve many questions that we had about how this precise cell-‐to-‐ cell regulation is carried out. With their works, many scientists across the world can apply their discoveries in various ways. Due to our profound genomic studies, we have been able to sequence many genomes of various organisms. With the research that we have done, we have seen many similar genetic sequences between yeast and certain human sequences, corresponding to our similar evolutionary ancestor. This has led many researchers to study human conditions by studying the yeast counterparts as model organisms, as Randy Schekman did in order to “identify certain genetic controllers in the cell’s transport system” (1). Cell Signaling Analysis AssignmentCell signaling can be classified as either mechanical or biochemical based on the type of the signal. Mechanical signals are the forces exerted on the cell and the forces produced by the cell. These forces can both be sensed and responded to by the cells. Biochemical signals are the biochemical molecules such as proteins, lipids, ions and gases. These signals can be categorized based on the distance between signaling and responder cells. Signaling within, between, and amongst cells is subdivided into the following classifications:Cell Signaling Analysis Essay Paper
Intracrine signals are produced by the target cell that stay within the target cell.
Autocrine signals are produced by the target cell, are secreted, and affect the target cell itself via receptors. Sometimes autocrine cells can target cells close by if they are the same type of cell as the emitting cell. An example of this are immune cells.
Juxtacrine signals target adjacent (touching) cells. These signals are transmitted along cell membranes via protein or lipid components integral to the membrane and are capable of affecting either the emitting cell or cells immediately adjacent.
Paracrine signals target cells in the vicinity of the emitting cell. Neurotransmitters represent an example.
Endocrine signals target distant cells. Endocrine cells produce hormones that travel through the blood to reach all parts of the body.Cell Signaling Analysis Essay Paper
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